POU6F1 Q14863

POU域，第6类，转录因子1 (脑特异性同源盒/POU域蛋白5) (Brain-5) (Brn-5) (mPOU同源盒蛋白)

功能描述

优先结合八聚体基序变体 (5'-ATGATAAT-3') 的转录因子。 {ECO:0000250}。

组织特异性

In the embryo, expressed exclusively in the developing brain, whereas in the adult its expression is restricted to brain, heart, skeletal muscle and lung. In the brain, the highest expression levels are found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum.

亚细胞定位

Nucleus