POLR2J P52435

DNA导向RNA聚合酶II亚基RPB11-a (RNA聚合酶II亚基B11-a) (RPB11a) (DNA导向RNA聚合酶II亚基J-1) (RNA聚合酶II 13.3 kDa亚基)

蛋白质信息 (UniProt)

DNA导向RNA聚合酶II亚基RPB11-a (RNA聚合酶II亚基B11-a) (RPB11a) (DNA导向RNA聚合酶II亚基J-1) (RNA聚合酶II 13.3 kDa亚基)

P52435

功能描述

RNA polymerase II (Pol II)的核心组分，这是一种DNA依赖性RNA聚合酶，以四种核糖核苷三磷酸为底物，合成mRNA前体和许多功能性非编码RNA。 {ECO:0000269|PubMed:27193682, ECO:0000269|PubMed:30190596, ECO:0000269|PubMed:37595871, ECO:0000269|PubMed:9852112}.

组织特异性

Ubiquitously expressed. High expression was found in heart and skeletal muscle.

亚细胞定位

Nucleus

关键词

3D-structure Acetylation Direct protein sequencing DNA-directed RNA polymerase Nucleus Proteomics identification Reference proteome Transcription

外部链接

UniProt: P52435

NCBI Gene

GeneCards