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PLA2G4D Q86XP0

胞质磷脂酶A2 delta (cPLA2-delta) (EC 3.1.1.4) (磷脂酶A2家族IVD)

蛋白质信息 (UniProt)

胞质磷脂酶A2 delta (cPLA2-delta) (EC 3.1.1.4) (磷脂酶A2家族IVD)

Q86XP0

功能描述

钙依赖性磷脂酶A2,选择性水解sn-2位的甘油磷脂 (PubMed:14709560)。对sn-2位的亚油酸具有偏好 (PubMed:14709560)。 {ECO:0000269|PubMed:14709560}。

组织特异性

Expressed in stratified squamous epithelia, such as those in skin and cervix, but not in other tissues (PubMed:14709560). Strongly expressed in the upper spinous layer of the psoriatic epidermis, expressed weakly and discontinuously in atopic dermatitis and mycosis fungoides, and not detected in the epidermis of normal skin (PubMed:14709560).

亚细胞定位

Cytoplasm, cytosol

关键词

3D-structure Alternative splicing Calcium Cytoplasm Hydrolase Lipid degradation Lipid metabolism Membrane Metal-binding Proteomics identification