PABPC1L Q4VXU2

多聚腺苷酸结合蛋白1样 (胚胎多聚(A)结合蛋白) (胞质多聚(A)结合蛋白1样)

蛋白质信息 (UniProt)

多聚腺苷酸结合蛋白1样 (胚胎多聚(A)结合蛋白) (胞质多聚(A)结合蛋白1样)

Q4VXU2

功能描述

参与卵母细胞成熟和早期胚胎发育的Poly(A)-binding protein (PubMed:37723834, PubMed:37052235)。它是卵母细胞中母源储存mRNA的细胞质mRNA多聚腺苷化和翻译激活所必需的 (By similarity)。 {ECO:0000250|UniProtKB:A2A5N3, ECO:0000269|PubMed:37052235, ECO:0000269|PubMed:37723834}。

组织特异性

Expressed in ovary and testis (PubMed:18716053). Also expressed in pancreas, liver and thymus, and at lower levels in other somatic tissues including brain and lung (PubMed:18716053).

亚细胞定位

Cytoplasm

关键词

Alternative splicing Cytoplasm Differentiation Disease variant Oogenesis Proteomics identification Reference proteome Repeat RNA-binding

外部链接

UniProt: Q4VXU2

NCBI Gene

GeneCards