P2Y嘌呤受体12 (P2Y12) (ADP-葡萄糖受体) (ADPG-R) (P2T(AC)) (P2Y(AC)) (P2Y(cyc)) (P2Y12血小板ADP受体) (P2Y(ADP)) (SP1999)
P2Y嘌呤受体12 (P2Y12) (ADP-葡萄糖受体) (ADPG-R) (P2T(AC)) (P2Y(AC)) (P2Y(cyc)) (P2Y12血小板ADP受体) (P2Y(ADP)) (SP1999)
Q9H244功能描述
ADP和ATP的受体，与抑制腺苷酸环化酶第二信使系统的G蛋白偶联。不被UDP和UTP激活。正常的血小板聚集和血液凝固所必需。 {ECO:0000269|PubMed:11104774, ECO:0000269|PubMed:11196645, ECO:0000269|PubMed:11502873, ECO:0000269|PubMed:12578987, ECO:0000269|PubMed:24670650, ECO:0000269|PubMed:24784220}.
组织特异性
Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain.
亚细胞定位
Cell membrane
关键词