OSGIN1 Q9UJX0

氧化应激诱导生长抑制因子1 (EC 1.14.13.-) (骨髓基质细胞源性生长抑制因子) (BMSC源性生长抑制因子) (卵巢、肾脏和肝脏蛋白38) (huOKL38) (妊娠诱导生长抑制因子OKL38)

蛋白质信息 (UniProt)

Q9UJX0

功能描述

单加氧酶催化活性 (PubMed:38442170)。参与胞质分裂的调控；促进RHOA活性，可能在胞质分裂后期作用于中间体局部 (PubMed:38442170)。单加氧酶活性参与在断裂前稳定子细胞间称为胞间桥的瞬时结构 (PubMed:38442170)。通过调节细胞死亡来调控分化和增殖 (PubMed:11459809, PubMed:14570898)。 {ECO:0000269|PubMed:11459809, ECO:0000269|PubMed:14570898, ECO:0000269|PubMed:38442170}。

组织特异性

Ubiquitous. Highest expression in the ovary, testis, kidney, skeletal muscle and liver (PubMed:11459809, PubMed:14570898).

亚细胞定位

Midbody

关键词

Developmental protein Differentiation FAD Flavoprotein Growth regulation Monooxygenase NADP Oxidoreductase Phosphoprotein Proteomics identification

外部链接

UniProt: Q9UJX0

NCBI Gene

GeneCards