OPTC Q9UBM4

视蛋白 (眼糖蛋白)

功能描述

抑制眼球玻璃体中的血管生成，从而抑制新血管生成 (By similarity)。结合胶原原纤维 (By similarity)。可能通过调节富含亮氨酸的小重复蛋白聚糖超家族的其他成员参与胶原纤维的组织 (By similarity)。 {ECO:0000250|UniProtKB:P58874, ECO:0000250|UniProtKB:Q920A0}。

组织特异性

Expressed in cartilage and synovial membranes (at protein level) (PubMed:18164633, PubMed:23845380). Expressed in the retina, iris, ligament, skin and fetal liver (at protein level) (PubMed:12019215, PubMed:25136834). Expressed in the retinal pigment epithelium (at protein level) (PubMed:25136834). Expressed in synovial fibroblasts and subchondral bone osteoblasts (PubMed:18164633).

亚细胞定位

Secreted, extracellular space, extracellular matrix