OCIAD1 Q9NX40

含OCIA结构域蛋白1 (卵巢癌免疫反应性抗原结构域包含蛋白1) (卵巢癌免疫反应性抗原)

功能描述

维持干细胞潜能 (By similarity)。增加STAT3磷酸化并控制ERK磷酸化 (By similarity)。可能作为支架，增加STAT3募集至内体 (By similarity)。参与卵巢癌中整合素介导的癌细胞粘附和集落形成 (PubMed:20515946)。 {ECO:0000250|UniProtKB:Q9CRD0, ECO:0000269|PubMed:20515946}。

组织特异性

Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland. Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord.

亚细胞定位

Endosome