NEBL O76041

小云蛋白 (肌动蛋白结合Z盘蛋白)

功能描述

结合actin，并在Z盘的组装中起重要作用。可能在心肌肌节中将肌节actin功能性地连接到desmin中间纤维 (PubMed:27733623)。 {ECO:0000269|PubMed:27733623}.; FUNCTION: [Isoform 2]: 可能在灶性粘附的组装中起作用。 {ECO:0000269|PubMed:15004028}.

组织特异性

Abundantly expressed in cardiac muscle, but not in skeletal or smooth muscle. Localized to Z-lines in cardiac cells and to dense bodies in nonmuscle cells. Isoform 2 is expressed in non-muscle cells such as in fibroblasts.

亚细胞定位

[Isoform 2]: Cytoplasm