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NAALAD2 Q9Y3Q0

N-乙酰化α连接酸性二肽酶2 (EC 3.4.17.21) (谷氨酸羧肽酶III) (GCPIII) (N-乙酰化α连接酸性二肽酶II) (NAALADase II)

蛋白质信息 (UniProt)

N-乙酰化α连接酸性二肽酶2 (EC 3.4.17.21) (谷氨酸羧肽酶III) (GCPIII) (N-乙酰化α连接酸性二肽酶II) (NAALADase II)

Q9Y3Q0

功能描述

具有N-乙酰化-α-连接酸性二肽酶(NAALADase)活性。亦表现出二肽基肽酶IV型活性。使肽类神经递质N-乙酰天冬氨酰谷氨酸失活。 {ECO:0000269|PubMed:10085079}。

组织特异性

Highest expression in the testis. Also found in ovary and spleen. Weak expression in prostate, heart and placenta. In brain, expressed in striatum, parietal cortex and ventral striatum with lower levels in hippocampus, brain stem, putamen and superior colliculus.

亚细胞定位

Cell membrane

关键词

3D-structure Alternative splicing Calcium Carboxypeptidase Cell membrane Dipeptidase Glycoprotein Hydrolase Membrane Metal-binding