MYOZ1 Q9NP98

肌泽宁-1 (钙沙蛋白-2) (细丝蛋白、辅肌动蛋白和Telethonin结合蛋白) (FATZ蛋白)

功能描述

Myozenins可能作为细胞内结合蛋白，参与连接Z盘蛋白（如alpha-actinin、gamma-filamin、TCAP/telethonin、LDB3/ZASP）并将calcineurin信号定位至肌节。在calcineurin信号的调节中起重要作用。可能在肌原纤维发生中起作用。

组织特异性

Expressed primarily in skeletal muscle. Detected at lower levels in heart, prostate and pancreas.

亚细胞定位

Nucleus. Cell projection, pseudopodium. Note=Localized to the nucleus and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. Colocalizes with ACTN2, FLNC and MYOT at the Z-lines of skeletal muscle.