MYLK2 Q9H1R3

骨骼/心肌肌球蛋白轻链激酶2 (MLCK2) (EC 2.7.11.18)

蛋白质信息 (UniProt)

骨骼/心肌肌球蛋白轻链激酶2 (MLCK2) (EC 2.7.11.18)

Q9H1R3

功能描述

与整体肌肉收缩水平和心脏功能有关。磷酸化肌球蛋白轻链N末端的一个特定丝氨酸。{ECO:0000269|PubMed:11733062}。

组织特异性

Heart and skeletal muscles. Increased expression in the apical tissue compared to the interventricular septal tissue.

亚细胞定位

Cytoplasm. Note=Colocalizes with phosphorylated myosin light chain (RLCP) at filaments of the myofibrils.

关键词

3D-structure Acetylation ATP-binding Calmodulin-binding Cardiomyopathy Cytoplasm Disease variant Kinase Nucleotide-binding Phosphoprotein

UniProt: Q9H1R3

NCBI Gene

GeneCards