黏蛋白-12 (MUC-12) (黏蛋白-11) (MUC-11)
黏蛋白-12 (MUC-12) (黏蛋白-11) (MUC-11)
Q9UKN1功能描述
参与上皮细胞保护、粘附调节和信号传导。可能参与上皮细胞生长调节。在肠上皮中受细胞因子TNF和TGF-beta刺激。 {ECO:0000269|PubMed:17058067}。
组织特异性
Ubiquitous, with higher expression in colon. Down-regulated in colorectal cancer as well as in the colon of patients with ulcerative colitis (UC) and Crohn's disease (CD).
亚细胞定位
Membrane
关键词