MT-ND4 P03905

NADH-泛醌氧化还原酶链4 (EC 7.1.1.2) (NADH脱氢酶亚基4)

蛋白质信息 (UniProt)

NADH-泛醌氧化还原酶链4 (EC 7.1.1.2) (NADH脱氢酶亚基4)

P03905

功能描述

线粒体膜呼吸链NADH脱氢酶（复合物I）的核心亚基，该酶利用泛醌作为电子受体，催化电子从NADH通过呼吸链传递 (PubMed:15250827, PubMed:8344246, PubMed:8644732)。对于复合物I的催化活性和组装至关重要 (PubMed:15250827, PubMed:8344246, PubMed:8644732)。 {ECO:0000269|PubMed:15250827, ECO:0000269|PubMed:8344246, ECO:0000269|PubMed:8644732}。

亚细胞定位

Mitochondrion inner membrane

关键词

3D-structure Disease variant Dystonia Electron transport Leber hereditary optic neuropathy MELAS syndrome Membrane Mitochondrion Mitochondrion inner membrane NAD

外部链接

UniProt: P03905

NCBI Gene

GeneCards