MSLN Q13421

间皮素 (CAK1抗原) (前巨核细胞增强因子前体) [裂解为: 巨核细胞增强因子 (MPF); 间皮素，裂解形式]

功能描述

膜锚定形式可能在细胞粘附中发挥作用。; FUNCTION: 巨核细胞增强因子(MPF)在体外增强巨核细胞集落形成。

组织特异性

Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).

亚细胞定位

Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus.; SUBCELLULAR LOCATION: [Megakaryocyte-potentiating factor]: Secreted.; SUBCELLULAR LOCATION: [Isoform 3]: Secreted.