MPV17 P39210

线粒体内膜蛋白Mpv17 (Protein Mpv17)

蛋白质信息 (UniProt)

线粒体内膜蛋白Mpv17 (Protein Mpv17)

P39210

功能描述

非选择性通道，在正常条件和氧化应激下调节膜电位，并参与线粒体稳态 (PubMed:25861990)。参与线粒体脱氧核糖核苷三磷酸 (dNTP) 库稳态和线粒体DNA (mtDNA) 维持 (PubMed:26760297)。可能参与活性氧代谢的调节和氧化磷酸化的控制 (By similarity)。 {ECO:0000250|UniProtKB:P19258, ECO:0000269|PubMed:25861990, ECO:0000269|PubMed:26760297}.

组织特异性

Ubiquitous. Expressed in pancreas, kidney, muscle, liver, lung, placenta, brain and heart.

亚细胞定位

Mitochondrion inner membrane

关键词

Charcot-Marie-Tooth disease Disease variant Membrane Mitochondrion Mitochondrion inner membrane Neurodegeneration Neuropathy Primary mitochondrial disease Proteomics identification Reference proteome

外部链接

UniProt: P39210

NCBI Gene

GeneCards