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MLLT11 Q13015

AF1q蛋白

蛋白质信息 (UniProt)

AF1q蛋白

Q13015

功能描述

转录因子TCF7的辅因子 (PubMed:26079538)。通过驱动多能造血祖细胞向T细胞命运分化,参与淋巴样发育的调节 (PubMed:21715312)。 {ECO:0000269|PubMed:21715312, ECO:0000269|PubMed:26079538}。

组织特异性

Expressed in myoepithelial cells of normal breast tissue (at protein level) (PubMed:26079538). Highly expressed in thymus (PubMed:7833468). Expressed in colon, small intestine, prostate and ovary. Not detected in peripheral blood lymphocytes and spleen (PubMed:7833468).

亚细胞定位

Nucleus

关键词

Chromosomal rearrangement Cytoplasm Cytoskeleton Nucleus Phosphoprotein Proteomics identification Proto-oncogene Reference proteome Ubl conjugation