MLDHR C0HLV8

PTEN上游开放阅读框MP31 (Micropeptide 31) (线粒体乳酸脱氢酶调节因子)

功能描述

通过与线粒体LDH竞争结合NAD(+)，抑制线粒体中lactate dehydrogenase (LDH)介导的lactate转化为pyruvate (PubMed:33406399)。也抑制细胞lactate利用 (PubMed:33406399)。 {ECO:0000269|PubMed:33406399}。

组织特异性

Expressed in brain (at protein level) (PubMed:33406399). Expressed at lower levels in glioblastomas than in normal brain tissue (at protein level) (PubMed:33406399).

亚细胞定位

Mitochondrion