中胚层诱导早期反应蛋白1 (早期反应1) (Er1) (Mi-er1) (hMi-er1)
中胚层诱导早期反应蛋白1 (早期反应1) (Er1) (Mi-er1) (hMi-er1)
Q8N108功能描述
转录抑制因子，调节包括SP1靶基因在内的多种基因的表达。可能通过招募HDAC1（一种参与染色质沉默的组蛋白去乙酰化酶）发挥作用。 {ECO:0000269|PubMed:12482978}。
组织特异性
Ubiquitously expressed, but at very low levels. However, consistent level of expression are observed in heart, testis, thyroid, ovary and adrenal gland. Transcripts are up-regulated in breast carcinoma cell lines and tumor.
亚细胞定位
[Isoform 1]: Nucleus.; SUBCELLULAR LOCATION: [Isoform 2]: Nucleus.; SUBCELLULAR LOCATION: [Isoform 3]: Nucleus.; SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm.; SUBCELLULAR LOCATION: [Isoform 5]: Cytoplasm.; SUBCELLULAR LOCATION: [Isoform 6]: Cytoplasm.
关键词