麦芽糖酶-葡糖淀粉酶 (Alpha-1,4-葡糖苷酶) (EC 3.2.1.20)
麦芽糖酶-葡糖淀粉酶 (Alpha-1,4-葡糖苷酶) (EC 3.2.1.20)
O43451功能描述
Alpha-(1,4) 外切葡糖苷酶，参与小肠中膳食淀粉寡糖的分解。以保留异头中心立体构型的方式切割线性糊精中非还原端alpha-(1,4)连接的葡萄糖残基 (PubMed:12547908, PubMed:18036614, PubMed:18356321, PubMed:22058037, PubMed:27480812)。主要水解含有二至七个葡萄糖残基的短链寡麦芽糖 (PubMed:12547908, PubMed:18036614, PubMed:18356321, PubMed:22058037, PubMed:27480812)。能以较低效率切割alpha-(1,2)、alpha-(1,3)和alpha-(1,6)糖苷键，而beta糖苷键通常不被水解 (PubMed:27480812)。 {ECO:0000269|PubMed:12547908, ECO:0000269|PubMed:18036614, ECO:0000269|PubMed:18356321, ECO:0000269|PubMed:22058037, ECO:0000269|PubMed:27480812}。
组织特异性
Broadly expressed. Highly expressed in small intestine. Expressed in granulocytes.
亚细胞定位
Apical cell membrane; Single-pass type II membrane protein. Note=Brush border.
关键词