MAGEA4 P43358

黑色素瘤相关抗原4 (癌/睾丸抗原1.4) (CT1.4) (MAGE-4抗原) (MAGE-41抗原) (MAGE-X2抗原)

功能描述

通过抑制G1期细胞周期停滞来调节细胞增殖 (PubMed:22842486)。同时也负向调节p53介导的细胞凋亡 (PubMed:22842486)。 {ECO:0000269|PubMed:22842486}。

组织特异性

Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta.