淋巴细胞抗原75 (Ly-75) (C型凝集素结构域家族13成员B) (DEC-205) (gp200-MR6) (CD抗原CD205)
淋巴细胞抗原75 (Ly-75) (C型凝集素结构域家族13成员B) (DEC-205) (gp200-MR6) (CD抗原CD205)
O60449功能描述
作为一种内吞受体，引导捕获的抗原从细胞外空间进入特化的抗原加工区室 (By similarity)。导致B淋巴细胞增殖减少。 {ECO:0000250}。
组织特异性
Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.
亚细胞定位
Membrane
关键词