LSM11 P83369

U7 snRNA相关Sm样蛋白LSm11

蛋白质信息 (UniProt)

U7 snRNA相关Sm样蛋白LSm11

P83369

功能描述

U7 snRNP复合物的组分，参与组蛋白3'端pre-mRNA加工 (PubMed:11574479, PubMed:16914750, PubMed:33230297)。过表达时增加U7 snRNA水平，但不增加组蛋白3'端pre-mRNA加工活性 (PubMed:11574479, PubMed:16914750)。细胞周期从G1期进入S期所必需 (By similarity)。特异性结合U7 snRNA的Sm结合位点 (PubMed:11574479, PubMed:16914750)。 {ECO:0000250|UniProtKB:Q8BUV6, ECO:0000269|PubMed:11574479, ECO:0000269|PubMed:16914750, ECO:0000269|PubMed:33230297}。

亚细胞定位

Nucleus

关键词

3D-structure Aicardi-Goutieres syndrome Direct protein sequencing Disease variant Isopeptide bond Methylation mRNA processing Nucleus Phosphoprotein Proteomics identification

外部链接

UniProt: P83369

NCBI Gene

GeneCards