内皮脂肪酶 (EC 3.1.1.3) (内皮细胞源性脂肪酶) (EDL) (EL) (磷脂酶A1) (EC 3.1.1.32)
内皮脂肪酶 (EC 3.1.1.3) (内皮细胞源性脂肪酶) (EDL) (EL) (磷脂酶A1) (EC 3.1.1.32)
Q9Y5X9功能描述
具有磷脂酶和甘油三酯脂肪酶活性 (PubMed:10192396, PubMed:10318835, PubMed:12032167)。作为磷脂酶的活性高于甘油三酯脂肪酶 (PubMed:12032167)。水解甘油三酯，包括带有短链脂肪酰基的甘油三酯（三丁酸甘油酯）和带有长链脂肪酰基的甘油三酯（三油酸甘油酯），对这两类底物的活性水平相似 (PubMed:12032167)。水解高密度脂蛋白 (HDL) 的效率高于其他脂蛋白 (PubMed:10192396, PubMed:12032167)。 {ECO:0000269|PubMed:10192396, ECO:0000269|PubMed:10318835, ECO:0000269|PubMed:12032167}。
组织特异性
High level of expression in the liver, placenta, lung, thyroid, kidney, testis and in the corpus luteum of the ovary. Expressed also in coronary artery endothelial cells, umbilical vein endothelial cells and in hepatocytes and osteosarcoma cell lines. Not detected in heart, brain and muscle.
亚细胞定位
Secreted
关键词