LCP1 P13796

Plastin-2 (L-plastin) (LC64P) (淋巴细胞胞质蛋白1) (LCP-1)

蛋白质信息 (UniProt)

Plastin-2 (L-plastin) (LC64P) (淋巴细胞胞质蛋白1) (LCP-1)

P13796

功能描述

肌动蛋白结合蛋白 (PubMed:16636079, PubMed:17294403, PubMed:28493397)。在通过TCR/CD3和CD2或CD28共刺激响应T细胞激活中发挥作用 (PubMed:17294403)。调节IL2RA/CD25和CD69的细胞表面表达 (PubMed:17294403)。 {ECO:0000269|PubMed:16636079, ECO:0000269|PubMed:17294403, ECO:0000269|PubMed:28493397}。

组织特异性

Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T-lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells.

亚细胞定位

Cytoplasm, cytoskeleton

关键词

3D-structure Acetylation Actin-binding Alternative splicing Calcium Cell junction Cell membrane Cell projection Chromosomal rearrangement Cytoplasm

外部链接

UniProt: P13796

NCBI Gene

GeneCards