KRTDAP P60985

角质形成细胞分化相关蛋白

功能描述

可能作为角质形成细胞分化的可溶性调节因子。可能在胚胎皮肤形态发生中发挥重要作用。 {ECO:0000269|PubMed:15140226}。

组织特异性

Highly expressed in skin and detected at lower levels in thymus. In skin, found exclusively in lamellar granules of granular keratinocytes and in the intracellular space of the stratum corneum. Also highly expressed in oral mucosa, tongue, esophagus, and stomach, and at much lower levels in bladder and uterus. Not detected in gastrointestinal mucosa.

亚细胞定位

Secreted