KRT75 O95678

角蛋白，II型细胞骨架75 (细胞角蛋白-75) (CK-75) (角蛋白-6毛囊) (hK6hf) (角蛋白-75) (K75) (II型角蛋白-K6hf) (II型角蛋白Kb18)

功能描述

在毛发和指甲形成中发挥核心作用。毛囊伴随层中角蛋白中间丝的必需组分。

组织特异性

Highly expressed in hair follicles from scalp. Specifically expressed in the of the hair companion layer follicle, a single layered band of flat and vertically oriented cells between the cuboidal outer root sheath (ORS) cells and the inner root sheath (IRS) that stretches from the lowermost bulb region to the isthmus of the follicle. Also expressed in medullated hairs. In nails, it is almost exclusively present in the nail bed (at protein level).