I型细胞骨架角蛋白25 (细胞角蛋白-25) (CK-25) (角蛋白-25) (K25) (角蛋白-25A) (K25A) (I型内根鞘特异性角蛋白-K25irs1)
I型细胞骨架角蛋白25 (细胞角蛋白-25) (CK-25) (角蛋白-25) (K25) (角蛋白-25A) (K25A) (I型内根鞘特异性角蛋白-K25irs1)
Q7Z3Z0功能描述
对于内根鞘(irs)中I型和II型角蛋白复合物的正确组装及角蛋白中间丝的形成至关重要 (By similarity)。在细胞骨架组织中发挥作用 (PubMed:26902920)。 {ECO:0000250|UniProtKB:Q8VCW2, ECO:0000269|PubMed:26902920}。
组织特异性
Strongly expressed in skin and scalp, and weak expression observed in thymus and tongue. In the hair follicle, expressed in Henle layer, Huxley layer and in the inner root sheath cuticle of the hair follicle. Expression extends from the bulb region up to the point of differentiation into the three layers. Also present in the medulla of beard hair (at protein level).
亚细胞定位
Cytoplasm
关键词