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KRT20 P35900

角蛋白,I型细胞骨架20 (细胞角蛋白-20) (CK-20) (角蛋白-20) (K20) (蛋白IT)

蛋白质信息 (UniProt)

角蛋白,I型细胞骨架20 (细胞角蛋白-20) (CK-20) (角蛋白-20) (K20) (蛋白IT)

P35900

功能描述

在维持肠上皮角蛋白丝排列中发挥重要作用。磷酸化后,在小肠粘蛋白分泌中发挥作用 (By similarity)。 {ECO:0000250, ECO:0000269|PubMed:12857878, ECO:0000269|PubMed:16608857}。

组织特异性

Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa.

亚细胞定位

Cytoplasm

关键词

Apoptosis Coiled coil Cytoplasm Direct protein sequencing Intermediate filament Keratin Phosphoprotein Proteomics identification Reference proteome