驱动蛋白样蛋白 KIF18B
驱动蛋白样蛋白 KIF18B
Q86Y91功能描述
与KIF2C形成复合物,构成有丝分裂细胞中主要的微管正端解聚活性。其主要作用可能是沿微管运输KIF2C和/或MAPRE1。{ECO:0000269|PubMed:20600703, ECO:0000269|PubMed:21820309}。
组织特异性
Shows a prominent expression in the amygdala.
亚细胞定位
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Present predominantly in the nucleus and to a lesser extent in the cytoplasm of interphase cells. During mitosis, found to be closely associated with astral microtubule plus ends emanating from the spindle pole during prometaphase and metaphase.
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