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KIF18B Q86Y91

驱动蛋白样蛋白 KIF18B

蛋白质信息 (UniProt)

驱动蛋白样蛋白 KIF18B

Q86Y91

功能描述

与KIF2C形成复合物,构成有丝分裂细胞中主要的微管正端解聚活性。其主要作用可能是沿微管运输KIF2C和/或MAPRE1。{ECO:0000269|PubMed:20600703, ECO:0000269|PubMed:21820309}。

组织特异性

Shows a prominent expression in the amygdala.

亚细胞定位

Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Present predominantly in the nucleus and to a lesser extent in the cytoplasm of interphase cells. During mitosis, found to be closely associated with astral microtubule plus ends emanating from the spindle pole during prometaphase and metaphase.

关键词

Alternative splicing ATP-binding Cell cycle Cell division Coiled coil Cytoplasm Cytoskeleton Microtubule Mitosis Motor protein