IMPG1 Q17R60

光感受器间基质蛋白聚糖1 (150 kDa光感受器间基质蛋白聚糖) (IPM-150) (视杆视锥相关唾液蛋白)

蛋白质信息 (UniProt)

光感受器间基质蛋白聚糖1 (150 kDa光感受器间基质蛋白聚糖) (IPM-150) (视杆视锥相关唾液蛋白)

Q17R60

功能描述

硫酸软骨素、肝素和透明质酸结合蛋白 (By similarity)。可能用于形成包含不溶性光感受器间基质的基本大分子支架 (PubMed:9813076)。 {ECO:0000250|UniProtKB:Q8JIR8, ECO:0000269|PubMed:9813076}。

组织特异性

Expressed in the retina (at protein level) (PubMed:10601738, PubMed:29777959). In the retina, specifically expressed by cone and rod photoreceptor cells (PubMed:9813076). Localizes to cone and rod photoreceptor cells surrounding the interphotoreceptor matrix of the retina (PubMed:9719680).

亚细胞定位

Cell projection, cilium, photoreceptor outer segment

关键词

Alternative splicing Cell projection Direct protein sequencing Disease variant Extracellular matrix Glycoprotein Heparin-binding Hyaluronic acid Proteomics identification Receptor

外部链接

UniProt: Q17R60

NCBI Gene

GeneCards