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HTR3A P46098

5-羟色胺受体3A (5-HT3-A) (5-HT3A) (5-羟色胺受体3) (5-HT-3) (5-HT3R) (血清素受体3A) (血清素门控离子通道受体)

蛋白质信息 (UniProt)

5-羟色胺受体3A (5-HT3-A) (5-HT3A) (5-羟色胺受体3) (5-HT-3) (5-HT3R) (血清素受体3A) (血清素门控离子通道受体)

P46098

功能描述

形成血清素(5-羟色胺/5-HT3)激活的阳离子选择性通道复合物,当被激活时,在神经元中引起快速去极化反应。 {ECO:0000269|PubMed:10521471, ECO:0000269|PubMed:12867984, ECO:0000269|PubMed:17392525, ECO:0000269|PubMed:9950429}。

组织特异性

Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta.

亚细胞定位

Postsynaptic cell membrane

关键词

3D-structure Alternative splicing Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane