HPSE2 Q8WWQ2

无活性乙酰肝素酶-2 (Hpa2)

功能描述

以高亲和力结合肝素和硫酸乙酰肝素，但缺乏乙酰肝素酶活性。抑制HPSE，可能通过竞争其底物（体外）。{ECO:0000269|PubMed:20576607}。

组织特异性

Widely expressed, with the highest expression in brain, mammary gland, prostate, small intestine, testis and uterus. In the central nervous system, expressed in the spinal cord, caudate nucleus, thalamus, substantia nigra, medulla oblongata, putamen and pons. In the urinary bladder, expressed in longitudinal and circular layers of detrusor muscle. Found both in normal and cancer tissues.

亚细胞定位

Secreted, extracellular space, extracellular matrix