HLA-DOA P06340

HLA II类组织相容性抗原，DOα链 (MHC DN-alpha) (MHC DZ alpha) (MHC II类抗原 DOA)

功能描述

功能：通过与B细胞中的HLA-DM分子相互作用，成为HLA II类限制性抗原呈递通路中的重要调节因子。改变HLA-DM的肽交换活性。

亚细胞定位

Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Complexes with HLA-DM molecule during intracellular transport and in endosomal/lysosomal compartments. Heterotetramerization is necessary to exit the ER.