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HACL2 A1L0T0

2-羟脂酰-CoA裂合酶2 (EC 4.1.2.-) (乙酰乳酸合酶样蛋白) (IlvB样蛋白)

蛋白质信息 (UniProt)

2-羟脂酰-CoA裂合酶2 (EC 4.1.2.-) (乙酰乳酸合酶样蛋白) (IlvB样蛋白)

A1L0T0

功能描述

内质网2-OH脂酰-CoA裂解酶，以硫胺素焦磷酸(TPP)依赖性方式参与脂肪酸α-氧化中的裂解（C1去除）反应。参与植物鞘氨醇降解途径。{ECO:0000269|PubMed:28289220}。

组织特异性

Expressed in all tissues tested, with highest expression in heart, pancreas and placenta.

亚细胞定位

Endoplasmic reticulum membrane

关键词

Endoplasmic reticulum Fatty acid metabolism Lipid metabolism Lyase Magnesium Membrane Metal-binding Proteomics identification Reference proteome Thiamine pyrophosphate

外部链接

UniProt: A1L0T0
NCBI Gene