GYG2 O15488

糖原蛋白-2 (GN-2) (GN2) (EC 2.4.1.186)

蛋白质信息 (UniProt)

糖原蛋白-2 (GN-2) (GN2) (EC 2.4.1.186)

O15488

功能描述

Glycogenin与glycogen synthase及glycogen branching enzyme共同参与glycogen生物合成过程。它催化形成短的alpha (1,4)-glucosyl链，该链通过glucose 1-O-tyrosyl键共价连接于内部tyrosine残基，这些链作为glycogen synthase催化的延伸反应的引物。 {ECO:0000269|PubMed:9346895, ECO:0000269|PubMed:9857012}。

组织特异性

Detected in liver (at protein level) (PubMed:9857012). Expressed preferentially in liver, heart, and pancreas (PubMed:9346895).

亚细胞定位

Cytoplasm

关键词

3D-structure Alternative splicing Cytoplasm Glycogen biosynthesis Glycoprotein Manganese Metal-binding Nucleus Phosphoprotein Proteomics identification

外部链接

UniProt: O15488

NCBI Gene

GeneCards