GPRC5B Q9NZH0

G蛋白偶联受体家族C第5组成员B (A-69G12.1) (视黄酸诱导基因2蛋白) (RAIG-2)

功能描述

参与细胞体积调节的G蛋白偶联受体。 {ECO:0000269|PubMed:37143309}。

组织特异性

Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte. According to PubMed:10945465, highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal cord as well as in dorsal root ganglia (DRG). Expressed in glia limitans, ependymal cells, astrocyte cell bodies, the perivascular region in astrocyte endfeet, but not in neurons (PubMed:37143309). In the periphery, expression levels are relatively low, compared to the CNS, with the strongest expression detected in pancreas, testis, uterus, and stomach.

亚细胞定位

Cell membrane