GPR87 Q9BY21

G蛋白偶联受体87 (G蛋白偶联受体95)

蛋白质信息 (UniProt)

G蛋白偶联受体87 (G蛋白偶联受体95)

Q9BY21

功能描述

溶血磷脂酸 (LPA) 的受体 (PubMed:17905198)。为响应 DNA 损伤的 p53/TP53 依赖性存活所必需 (PubMed:19602589)。促进 Hippo-YAP 信号通路，从而通过调节己糖激酶-2/HK2 来调控糖酵解和氧化应激产生 (PubMed:35843477)。 {ECO:0000269|PubMed:17905198, ECO:0000269|PubMed:19602589, ECO:0000269|PubMed:35843477}。

组织特异性

Expressed in placenta and prostate. Weaker expression in thymus. Not expressed in thalamus, hippocampus, pons or cerebellum. Overexpressed in squamous cell carcinoma of the lung.

亚细胞定位

Cell membrane

关键词

Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Proteomics identification Receptor Reference proteome Transducer Transmembrane

外部链接

UniProt: Q9BY21

NCBI Gene

GeneCards