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GPR22 Q99680

G蛋白偶联受体22

蛋白质信息 (UniProt)

G蛋白偶联受体22

Q99680

功能描述

孤儿G蛋白偶联受体。似乎通过G(i)/G(o)介导的途径起作用 (PubMed:18539757)。可能参与纤毛发生 (By similarity)。 {ECO:0000250|UniProtKB:A0A2R9YJI3, ECO:0000269|PubMed:18539757}。

组织特异性

High expression in adult and fetal heart tissue (PubMed:18539757). Expressed in the brain, with enrichment in the accumbens, amygdala, cerebellum, cortex, and hippocampus regions (PubMed:18539757, PubMed:9073069).

亚细胞定位

Cell membrane

关键词

Cell membrane Cilium biogenesis/degradation G-protein coupled receptor Glycoprotein Membrane Proteomics identification Receptor Reference proteome Transducer Transmembrane