多肽N-乙酰半乳糖胺转移酶9 (EC 2.4.1.41) (多肽GalNAc转移酶9) (GalNAc-T9) (pp-GaNTase 9) (蛋白质-UDP乙酰半乳糖胺转移酶9) (UDP-GalNAc:多肽N-乙酰半乳糖胺转移酶9)
多肽N-乙酰半乳糖胺转移酶9 (EC 2.4.1.41) (多肽GalNAc转移酶9) (GalNAc-T9) (pp-GaNTase 9) (蛋白质-UDP乙酰半乳糖胺转移酶9) (UDP-GalNAc:多肽N-乙酰半乳糖胺转移酶9)
Q9HCQ5功能描述
催化O-连接寡糖生物合成中的起始反应，即将N-乙酰-D-半乳糖胺残基转移至protein受体上的丝氨酸或苏氨酸残基。不糖基化apomucin或SDC3。 {ECO:0000269|PubMed:10978536, ECO:0000269|PubMed:12407114}。
组织特异性
Specifically expressed in brain. Not expressed in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte. In brain, it is expressed in cerebellum, frontal lobe, temporal lobe, putamen and spinal cord, weakly expressed in cerebral cortex. Not expressed in medulla and occipital pole.
亚细胞定位
Golgi apparatus membrane
关键词