FYN结合蛋白1 (粘附和脱颗粒促进接头蛋白) (ADAP) (FYB-120/130) (p120/p130) (FYN-T结合蛋白) (SLAP-130) (SLP-76相关磷蛋白)
FYN结合蛋白1 (粘附和脱颗粒促进接头蛋白) (ADAP) (FYB-120/130) (p120/p130) (FYN-T结合蛋白) (SLAP-130) (SLP-76相关磷蛋白)
O15117功能描述
在T细胞中作为FYN和LCP2信号级联反应的接头蛋白 (By similarity)。可能在连接T细胞信号传导与肌动蛋白细胞骨架重塑中发挥作用 (PubMed:10747096, PubMed:16980616)。调节IL2的表达 (By similarity)。参与血小板活化 (By similarity)。防止SKAP1和SKAP2的降解 (PubMed:15849195)。可能参与肥大细胞中高亲和力免疫球蛋白epsilon受体信号传导 (By similarity)。 {ECO:0000250|UniProtKB:D3ZIE4, ECO:0000250|UniProtKB:O35601, ECO:0000269|PubMed:10747096, ECO:0000269|PubMed:15849195, ECO:0000269|PubMed:16980616}.
组织特异性
Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues.
亚细胞定位
Cytoplasm
关键词