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FSD1 Q9BTV5

含纤连蛋白III型和SPRY结构域蛋白1 (MID1相关蛋白1) (微管相关蛋白GLFND)

蛋白质信息 (UniProt)

含纤连蛋白III型和SPRY结构域蛋白1 (MID1相关蛋白1) (微管相关蛋白GLFND)

Q9BTV5

功能描述

可能参与微管组织和稳定。 {ECO:0000269|PubMed:12154070, ECO:0000269|PubMed:12445389}。

组织特异性

Highly expressed in brain tissues, including cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Lower expression in spinal cord.

亚细胞定位

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Cleavage furrow. Note=Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associate with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle.

关键词

Cell cycle Cell division Coiled coil Cytoplasm Cytoskeleton Methylation Microtubule Mitosis Nucleus Proteomics identification