FLG P20930

丝聚蛋白

功能描述

聚集角蛋白中间丝，并在哺乳动物表皮终末分化过程中促进中间丝之间二硫键的形成。

组织特异性

Expressed in skin, thymus, stomach, tonsils, testis, placenta, kidney, pancreas, mammary gland, bladder, thyroid, salivary gland and trachea, but not detected in heart, brain, liver, lung, bone marrow, small intestine, spleen, prostate, colon, or adrenal gland (PubMed:19384417). In the skin, mainly expressed in stratum granulosum of the epidermis (PubMed:1429717, PubMed:19384417).

亚细胞定位

Cytoplasmic granule