FILIP1 Q7Z7B0

细丝蛋白A相互作用蛋白1 (FILIP)

功能描述

通过肌动蛋白-A/F-肌动蛋白轴发挥作用，控制新皮质细胞从脑室区迁移的起始。可能能够诱导肌动蛋白-A的降解。 {ECO:0000250|UniProtKB:Q8K4T4}。

组织特异性

Moderately expressed in adult heart and brain. Weakly expressed in lung, skeletal muscle, ovary, testis, kidney, and fetal brain, and hardly detectable in liver, pancreas, spleen, and fetal liver. Within brain, moderate expression is found in amygdala and caudate nucleus (PubMed:10574462). Expressed in skin fibroblasts.

亚细胞定位

Cytoplasm, cytoskeleton