FCAR P24071

免疫球蛋白α Fc受体 (IgA Fc受体) (CD抗原 CD89)

功能描述

结合免疫球蛋白alpha的Fc区。介导包括细胞因子产生在内的多种功能。 {ECO:0000269|PubMed:12768205}。

组织特异性

Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.

亚细胞定位

[Isoform A.1]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform A.2]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform A.3]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform B]: Secreted.; SUBCELLULAR LOCATION: [Isoform B-delta-S2]: Secreted.