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F11 P03951

凝血因子XI (FXI) (EC 3.4.21.27) (血浆凝血活酶前体) (PTA) [裂解为：凝血因子XIa重链；凝血因子XIa轻链]

蛋白质信息 (UniProt)

凝血因子XI (FXI) (EC 3.4.21.27) (血浆凝血活酶前体) (PTA) [裂解为：凝血因子XIa重链；凝血因子XIa轻链]

P03951

功能描述

因子XI通过激活因子IX触发血液凝固内源性途径的中期阶段。 {ECO:0000269|PubMed:22961984}。

组织特异性

Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells.

亚细胞定位

Secreted.

关键词

3D-structure Alternative splicing Blood coagulation Direct protein sequencing Disease variant Disulfide bond Glycoprotein Hemostasis Heparin-binding Hydrolase

外部链接

UniProt: P03951
NCBI Gene