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ERC1 Q8IUD2

ELKS/Rab6相互作用/CAST家族成员1 (ERC-1) (Rab6相互作用蛋白2)

蛋白质信息 (UniProt)

ELKS/Rab6相互作用/CAST家族成员1 (ERC-1) (Rab6相互作用蛋白2)

Q8IUD2

功能描述

IKK复合物的调节亚基。可能将IkappaBalpha/NFKBIA招募到复合物中。可能参与神经末梢活性区(CAZ)细胞基质基质的组织,该区域调节神经递质释放。可能参与CAZ处的囊泡运输。可能参与Rab-6调节的内体到高尔基体运输。 {ECO:0000269|PubMed:15218148}。

组织特异性

Widely expressed. Isoform 2 and isoform 4 are abundantly expressed in brain. Isoform 1 and isoform 3 are predominantly expressed in testis and thyroid, and isoform 1 predominates in other tissues tested.

亚细胞定位

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

关键词

Acetylation Alternative splicing Cell junction Cell membrane Cell projection Chromosomal rearrangement Coiled coil Cytoplasm Cytoskeleton Direct protein sequencing