细胞外基质蛋白1 (分泌成分p85)
细胞外基质蛋白1 (分泌成分p85)
Q16610功能描述
作为骨矿化的负调节因子参与软骨内骨形成。刺激内皮细胞增殖并促进血管生成。抑制MMP9蛋白水解活性。 {ECO:0000269|PubMed:11165938, ECO:0000269|PubMed:11292659, ECO:0000269|PubMed:16512877}。
组织特异性
Expressed in breast cancer tissues. Little or no expression observed in normal breast tissues. Expressed in skin; wide expression is observed throughout the dermis with minimal expression in the epidermis.
亚细胞定位
Secreted, extracellular space, extracellular matrix.
关键词