DPY19L2 Q6NUT2

推测的C-甘露糖基转移酶DPY19L2 (EC 2.4.1.-) (Dpy-19样蛋白2) (蛋白质dpy-19同源物2)

蛋白质信息 (UniProt)

推测的C-甘露糖基转移酶DPY19L2 (EC 2.4.1.-) (Dpy-19样蛋白2) (蛋白质dpy-19同源物2)

Q6NUT2

功能描述

可能的C-甘露糖基转移酶，介导靶蛋白上色氨酸残基的C-甘露糖基化。 {ECO:0000250|UniProtKB:P34413}.; FUNCTION: 精子发生过程中精子头部延长和顶体形成所必需的 (PubMed:21397063, PubMed:21397064)。也在顶体附着于核膜中发挥作用 (By similarity)。 {ECO:0000250|UniProtKB:P0CW70, ECO:0000269|PubMed:21397063, ECO:0000269|PubMed:21397064}.

组织特异性

Widely expressed with high expression in testis. Not detectable in ejaculated sperm (at protein level).

亚细胞定位

Nucleus inner membrane

关键词

Alternative splicing Developmental protein Differentiation Disease variant Glycosyltransferase Membrane Nucleus Proteomics identification Reference proteome Spermatogenesis

外部链接

UniProt: Q6NUT2

NCBI Gene

GeneCards