DIP2B Q9P265

Disco相互作用蛋白2同源物B (DIP2同源物B)

功能描述

负向调节轴突生长，是正常突触传递所必需的。轴突极性的调节不需要。促进α-微管蛋白的乙酰化。 {ECO:0000250|UniProtKB:Q3UH60}。

组织特异性

Moderately expressed in adult brain, placenta, skeletal muscle, heart, kidney, pancreas, lung, spleen and colon. Expression was weaker in adult liver, kidney, spleen, and ovary, and in fetal brain and liver. In the brain, it is expressed in the cerebral cortex; the frontal, parietal, occipital and temporal lobes; the paracentral gyrus; the pons; the corpus callosum and the hippocampus. Highest expression levels in the brain were found in the cerebral cortex and the frontal and parietal lobes.

亚细胞定位

Cell projection, dendrite